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Cushing Syndrome
Symptoms

Most people with Cushing syndrome will have:

  • Upper body obesity (above the waist) and thin arms and legs
  • Round, red, full face (moon face)
  • Slow growth rate in children
Skin changes that are often seen:
  • Acne or skin infections
  • Purple marks (1/2 inch or more wide) called striae on the skin of the abdomen, thighs, and breasts
  • Thin skin with easy bruising
Muscle and bone changes include:
  • Backache, which occurs with routine activities
  • Bone pain or tenderness
  • Collection of fat between the shoulders (buffalo hump)
  • Thinning of the bones, which leads to rib and spine fractures
  • Weak muscles
Women with Cushing syndrome often have:
  • Excess hair growth on the face, neck, chest, abdomen, and thighs
  • Menstrual cycle becomes irregular or stops
Men may have:
  • Decreased fertility
  • Decreased or no desire for sex
  • Impotence
Other symptoms that may occur with this disease:
  • Mental changes, such as depression, anxiety, or changes in behavior
  • Fatigue
  • Headache
  • High blood pressure
  • Increased thirst and urination

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